Blog
Articles on longevity, preventive medicine and wellbeing.
Omega-3 and biological aging: what the DO-HEALTH clock data really show
The DO-HEALTH trial found small epigenetic-clock signals with omega-3, vitamin D and exercise. Here is what changed, what did not, and how to decide safely.
Microplastics in the Brain: What the Evidence Means and What to Do
A practical 2026 guide to microplastics in the brain: what Nature Medicine found, why the methods debate matters, and how to lower exposure without fear.
p16, Senescence and Senolytics: What the Antibody Problem Really Means
The confusion between p16INK4a and p16-ARC/ARPC5 does not collapse senescence biology, but it does raise the bar for biomarker validation before anyone talks about senolytics or anti-aging treatments.
Longevity Diet, Methionine and GLP-1: What the New Study Shows
A new Cell Metabolism study links a methionine-adjusted longevity diet with GLP-1, FGF21 and lower frailty in mice. The clinical takeaway is not to copy a mouse diet, but to personalize protein, muscle and metabolic risk.
Rapamycin for longevity: why it matters and why it is not a harmless biohack
Rapamycin is one of the most compelling molecules in geroscience, but it is also a prescription immunosuppressant. Here is what human trials show, what remains unproven and what should be monitored.
Longevity Drugs: What the New Nature Aging Paper Really Shows
A Nature Aging study maps existing drugs against the hallmarks of aging. Here is what it means, what it does not prove, and why self-medication is the wrong takeaway.
Biological Aging Speed: What a 0.57x Clock Result Really Means
Biological aging speed is not a promise to live twice as long. Here is how to read DunedinPACE, GrimAge and PhenoAge with medical context.
Midjourney's Ultrasound Scanner: Preventive Longevity Frontier or Medical Hype?
Midjourney Medical has announced a water-based full-body ultrasound scanner, not an MRI. The most credible near-term use is body composition and longitudinal tracking, while diagnostic claims still need clinical validation.
Lack of Natural Light at Work: Fatigue, Mood, Vitamin D and Sleep
Lack of natural light at work can affect sleep, energy, fatigue, mood and real outdoor exposure for vitamin D. Here is how to measure and fix it.
Menopause at Work: The Invisible Cost of Ignoring Women's Health
Menopause at work is not a cosmetic benefit: broken sleep, brain fog, hot flashes, anxiety, pain and shame can affect productivity, absence and retention.
Best Residential Longevity Clinics in Europe: 2026 Comparison Guide
A practical 2026 comparison of Europe's leading longevity clinics, from Clinique La Prairie and SHA to Buchinger, Lanserhof, VIVAMAYR, Chenot, ZEM and Progevita.
Longevity clinic in Spain: Valencia, near Madrid, and how to choose a medical program
A practical guide to choosing a longevity clinic in Spain, Valencia or near Madrid: medical criteria, clinic models, pricing, FAQs and when Progevita makes sense.
Arthritis prevention and joint health: inflammation, movement and Mediterranean lifestyle
Joint health is not built by one supplement. It depends on inflammation, strength, body composition, vitamin D status, sleep, Mediterranean nutrition and well-dosed movement.
Sedentary lifestyle and health pillars: find what is missing before optimizing
Before supplements, advanced testing or biohacking, identify the missing pillar: movement, strength, sleep, food, alcohol/tobacco and preventive biomarkers.
Sports recovery after 40: adaptation vs accumulated fatigue
How to separate adaptation from accumulated fatigue after 40: sleep, load, strength, nutrition, HRV, biomarkers and when to back off.
Menopause Brain Fog: Memory, Sleep, Estrogen and What to Check
Updated 2026: menopause brain fog often combines sleep disruption, estrogen fluctuation, stress, iron, thyroid, B12 and glucose. What to check and when to seek help.
Strength by life stage: squat, chair stand and functional longevity
How to train strength in your 40s, 50s, 60s and beyond: squat pattern, chair stand test, sarcopenia, metabolic health and functional longevity.
Perimenopause and blood tests: what to measure before blaming hormones
What blood tests to consider in perimenopause: FSH and estradiol limits, thyroid, ferritin, B12, vitamin D, lipids, glucose, insulin and inflammation.
Joint pain in menopause: tendons, frozen shoulder and smart training
Joint pain in menopause: why tendons, frozen shoulder and stiffness appear, what red flags to watch and how to train without making it worse.
Strength training in menopause: muscle, bone and metabolism
Why strength training matters in menopause for muscle, bone, metabolism and body composition. How to start, what to measure and when clinical supervision helps.
VO₂ max after 40: how to improve it without burnout or injury
What a VO2 max of 40 means in your 40s, 50s or 60s, how to read watch estimates vs clinical testing, and how to improve with zone 2, intervals, strength and recovery.
Sports pain after 40: padel, running and how to stay active without making it worse
Padel elbow pain, tennis elbow, golfer’s elbow and runner’s knee after 40: how to adjust load, strength and recovery without stopping blindly.
Forest bathing and stress: what the science supports — and what it does not
Forest bathing and green social prescribing may support stress recovery and mild anxiety symptoms. 2026 evidence, limits and a measurable protocol.
Recovery biomarkers for athletes: what to measure — and what not to overinterpret
A practical guide to athlete recovery biomarkers: HRV, ferritin, CK, cortisol, inflammation, blood tests and the real limits of overtraining diagnosis.
Menopause hormone therapy in 2026: what changed, what did not, and how to decide safely
Menopause hormone therapy is being reappraised: less inherited fear from WHI, more clinical selection, and one core rule for women’s healthspan: timing, route and risk profile matter.
Personalized Longevity Protocols: Evidence Guide
An evidence-based guide to personalized longevity protocols: which biomarkers matter, what interventions are supported, and how to avoid generic anti-aging stacks.
Longevity retreat in Spain: how to choose a medical health retreat near Madrid
A practical guide to comparing longevity retreats, health retreats and luxury wellness resorts in Spain: medical criteria, evidence, pricing and when Progevita makes sense.
What Is Biohacking? How to Tell Science from Wellness Marketing
What is biohacking? A 2026 clinical guide to separate evidence from wellness marketing, with prudent dosing, metrics, risks and a checklist.
Therapeutic Fasting and Longevity: Benefits, Risks and When Medical Supervision Matters
What science says about therapeutic fasting, periodic fasting and longevity: potential benefits, risks, contraindications and how supervised protocols work.
High ApoB: What It Means, Target Levels and How to Lower It
High ApoB can reveal cardiovascular risk that standard LDL cholesterol may miss. Learn what ApoB measures, which target levels clinicians use and how to reduce risk safely.
High Lipoprotein(a) / Lp(a): What It Means, Cardiovascular Risk and What to Do
High lipoprotein(a), or high Lp(a), is an inherited cardiovascular risk factor often missed in basic cholesterol panels. Learn when to test it, how to interpret it and what to do if it is elevated.
Telomeres and aging: what they are, why they shorten, and what longevity science actually says
A clear, evidence-based guide to telomeres, aging, telomerase, telomere tests and what lifestyle or clinical interventions can realistically change.
What is BDNF? The brain fertilizer that helps memory age better
BDNF is a key protein for neuroplasticity, memory and neuronal survival. Here is what it does, how it changes with aging and which habits raise it with evidence.
Biological age: what it is and how to measure it
Biological age estimates how your body is aging compared with your chronological age. A clear guide to epigenetic clocks, biomarkers and test limits.
Hyperbaric Chamber and Longevity: Real Benefits, Risks and Limits
Can a hyperbaric chamber slow aging? A clear review of telomeres, senescent cells, VO2 max, safety, soft chambers and when HBOT makes sense.
VO2 max and longevity: age values, evidence and how to improve it
VO2 max is not just an athlete metric: updated evidence, age values, clinical testing and training guidance to improve cardiorespiratory capacity.
Heart rate variability (HRV): meaning, measurement and how to improve it
Heart rate variability is not a health score. It is a signal of how your nervous system adapts to sleep, stress, training load, alcohol, illness and recovery. Learn normal ranges by age, how to measure it, read trends and improve your baseline.
Sarcopenia: diagnosis, treatment and how to slow muscle loss
Sarcopenia is the progressive loss of muscle strength, mass and function with age. Learn symptoms, diagnosis, treatment and how to protect muscle during weight loss.
Metformin for Longevity: Should Healthy Adults Take It?
Updated June 21, 2026: metformin for longevity, TAME status, no validated anti-aging dosage, B12, muscle risks and medical supervision.
Melatonin and Aging: Does It Help Sleep or Longevity?
Does melatonin slow aging or mainly help sleep timing? A clear 2026 guide to benefits, dose timing, side effects and interactions.
Gut microbiome and longevity: inflammation, brain aging and what to measure
How the gut microbiome connects with longevity, inflammation and brain aging; what centenarian studies, tests, probiotics and biomarkers can actually tell you.
Menopause and Longevity: When HRT Protects Your Healthspan
Menopause changes bone, muscle, sleep, and cardiovascular risk. Here you can see when HRT makes sense, what it may improve, and what to measure before deciding.
How Much Does a Longevity Clinic Cost: 2026 Price Guide
Short answer: €500 to €1,500 per night for integrated clinics, €3,000 to €8,000 per night for premium operators, and €5,000 to €15,000 for diagnostics-only centers without accommodation. Includes Progevita's published prices updated in May 2026.
Why Valencia Is Becoming a Longevity Hub in Europe
Valencia combines Mediterranean nutrition, international access, natural surroundings and serious medical infrastructure. That is how a real longevity hub is built.
Healthspan vs lifespan: why living longer isn't enough
Healthspan is the period of life spent in good health. Global evidence now measures an average 9.6-year gap; in Spain it is roughly 12. How to interpret HALE, Healthy Life Years and biomarkers without mixing them up.
The 12 Hallmarks of Aging: What They Are and What You Can Do About Each One
The hallmarks of aging are 12 biological processes that drive age-related decline. From genomic instability to dysbiosis, we review the evidence and the interventions available today.
How to Choose a Longevity Clinic: 10 Criteria You Must Evaluate
The longevity market grows 8% per year, but not all clinics deliver the same value. These 10 criteria help you tell evidence-based medicine from marketing dressed up as science.
Senolytics: the science of eliminating the zombie cells that age you
Senolytics selectively destroy senescent cells that accelerate aging. From mice to the first human trials: what the science says and what you can do today.
Intermittent Fasting and Autophagy: Your Science-Based Guide to Cellular Cleanup
Autophagy is the cellular recycling system that removes damaged proteins, broken mitochondria and pathogens. Intermittent fasting is its most powerful natural trigger. A guide with protocols, studies and strategies to integrate it into your longevity plan.
Menopause and Weight Gain: Why It Happens and What Actually Works
Menopause isn't just hot flashes. Hormonal changes shift fat to your belly, reduce muscle mass, and alter your metabolism. Here's why you're gaining weight—and what science says actually works.
Therapeutic Fasting: What It Is, How It Works and What the Science Says
Therapeutic fasting isn't a diet — it's a medically supervised metabolic reset that activates autophagy, improves insulin sensitivity, and reduces inflammation. Complete guide on fasting types, biological mechanisms (AMPK, mTOR, sirtuins), evidence-backed benefits, contraindications, and how we apply it at Progevita.
Volcanic Water and Longevity: The Science of Mineral Balneotherapy
Volcanic water and balneotherapy: evidence for pain, stress, sleep and inflammation, what dosing studies use, and what not to promise.
Epigenetic Clocks: Biological Age vs Chronological Age
Epigenetic clocks measure your real biological age via DNA methylation. How Horvath, GrimAge and DunedinPACE work — and how to slow your aging rate.
Inflammaging: Chronic Inflammation and Accelerated Aging
What is inflammaging, how it ages you from within, and science-backed strategies to slow it down. Complete guide with biomarkers, tests and treatments.
Anti-Inflammatory Diet: Evidence-Based Guide for Longevity
An anti-inflammatory diet reduces chronic inflammation markers linked to aging. Evidence-based guide: foods, mechanisms, Mediterranean weekly menu, and integration with medical treatments.
What Is a Longevity Clinic? Tests, Costs and Medical Criteria
A medical longevity clinic measures biomarkers, fitness, body composition and risk before symptoms appear. Learn costs, treatments, follow-up and how to choose safely.
Vive Más 2026: longevity retreat with Marcos Vázquez at Progevita
Inside Vive Más 2026: four days of science, training and health assessment with Marcos Vázquez (Fitness Revolucionario), Borja Bandera, Matías Mut and Antonio Valenzuela at our health resort in Valencia, Spain.
Perimenopause: symptoms, duration, red flags and what to do
Perimenopause symptoms can include changing cycles, fatigue, hot flashes, broken sleep, brain fog, joint pain and sexual changes. Learn red flags, tests and treatments.
Preventive Medicine: What It Is, Key Tests and Why It Matters
Preventive medicine stops diseases before they start, catches them early, and reduces their impact. Learn how it works, its four levels, and how it connects to longevity medicine.
Cellular Senescence: What It Is and How It Drives Aging
Cellular senescence is the state in which a cell permanently stops dividing but does not die, instead releasing inflammatory signals that damage surrounding tissue and accelerate aging.
Sirtuins: What They Are, NAD+ Link and Human Evidence
What sirtuins are, how they depend on NAD+, and what human evidence says about exercise, fasting and longevity. A SIRT1-7 guide with biomarkers and real limits.
Mitochondrial Dysfunction and Aging: What Happens Inside Your Energy Factories
Mitochondrial dysfunction is the progressive loss of ATP production efficiency that occurs with age, accompanied by increased oxidative stress and chronic inflammation. It is one of the 12 hallmarks of aging.
Therapeutic Plasma Exchange (TPE): Cost, Benefits, Risks and Evidence
Medical guide to therapeutic plasma exchange (TPE): cost, plasmapheresis price factors, procedure, benefits, risks, recovery, established indications and cautious longevity evidence.
Plasmapheresis cost, safety and procedure: what to expect
What affects plasmapheresis cost, how the procedure works step by step, what safety checks matter and what to ask before booking.
NAD+ Therapy: Benefits, Risks and Evidence
NAD+ therapy aims to increase availability of a coenzyme that declines with age and influences energy, DNA repair, and mitochondrial function. A practical guide to uses, routes, costs, and the limits of human evidence.
Ozone Therapy Benefits: Evidence, Risks and What to Expect
A medical guide to ozone therapy benefits, evidence for pain and wounds, safety concerns, regulatory limits, contraindications and what to ask before treatment.
Longevity Biomarkers: What to Track, How Often and Why
Which biomarkers to track to see how you are actually aging, how often to repeat them, and which ones matter most for healthspan and risk.
The Impact Project X Progevita
In a business environment shaped by speed, uncertainty, and sustained demand, companies are seeking to strengthen leadership from a more human, healthy, and strategic perspective.
The Coolest Longevity & Health Event of the Year Lands at Progevita (Valencia): LBF7 Spain
From September 22–29, 2025, the Longevity Biotech Fellowship (LBF) comes to Spain, turning Balneario de Cofrentes – Progevita into the international hub of longevity.
A Special Retreat with Elena Devís: Science, Mindfulness and Longevity at Progēvita
A few weeks ago, we hosted a truly special retreat at Progēvita in collaboration with Elena Devís, founder of Positivamente Presente. For the 26 participants, it was far more than a medical program.
Why we launch Progēvita
My parents are physicians and have been running a large family-owned clinic for 30 years. When I incorporated to the family business already 15 years ago, I agreed with my father that I would not just operate the business he had founded but make it my vision.
Don't die
For some people Bryan Johnson might be an eccentric millionaire, his methodology might be questionable, even his business model is dubious, but over the last few years he has become an incredible asset to the longevity field.